晚期不可切除非小细胞肺癌病例分享一例(腺癌)
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">病例介绍</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"> <span style="color: black;">病人</span> 男 65岁 抽烟30余年,近期因“咳嗽、咯血伴<span style="color: black;">呼气</span>困难1月余”入院;<span style="color: black;">病人</span>自诉,活动后<span style="color: black;">显著</span><span style="color: black;">呼气</span>困难,偶有咯血;查体:右肺<span style="color: black;">呼气</span>音<span style="color: black;">显著</span>减弱;</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">影像学<span style="color: black;">检测</span></p>
<div style="color: black; text-align: left; margin-bottom: 10px;"><img src="https://pic3.zhimg.com/80/v2-6086ab0db87c4d0246f982103de336de_720w.webp" style="width: 50%; margin-bottom: 20px;"></div>
<div style="color: black; text-align: left; margin-bottom: 10px;"><img src="https://pic4.zhimg.com/80/v2-09a0b0c1f646f159ccbf9fa51d54454b_720w.webp" style="width: 50%; margin-bottom: 20px;"></div>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">病人</span>入院后行胸部CT<span style="color: black;">检测</span><span style="color: black;">发掘</span>:双肺占位,右侧<span style="color: black;">位置于</span>肺门处,肿块<span style="color: black;">很强</span>,包绕血管。从CT片<span style="color: black;">能够</span>看到阻塞性肺炎。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">病情分析</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">影像学表现如上两张<span style="color: black;">照片</span>所示;患者症状与影像学表现一致;专业<span style="color: black;">大夫</span>一看便知;<span style="color: black;">思虑</span>肿瘤;且分期较晚,<span style="color: black;">病人</span>已失去手术机会。好在<span style="color: black;">病人</span>经经查未<span style="color: black;">发掘</span>远处转移<span style="color: black;">状况</span>;只能<span style="color: black;">选取</span>内科保守治疗,<span style="color: black;">因此呢</span><span style="color: black;">日前</span>首要任务是<span style="color: black;">知道</span>诊断。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">治疗经过</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">争取<span style="color: black;">病人</span>意见后于当天给<span style="color: black;">病人</span>进行纤维支气管镜<span style="color: black;">检测</span>及取材活检,于右肺下叶支气管开口处见到简润生长肿瘤,已突破气管壁,肿瘤呈菜<span style="color: black;">花招</span>生长,表面触之易<span style="color: black;">流血</span>,气管内<span style="color: black;">海量</span>粘稠痰液;于肿块表面取组织活检;当时未留下照片及图像资料;只能文字描述向<span style="color: black;">大众</span>介绍。经过2天等待以后,病理科给<span style="color: black;">报答</span>的结果是:查见恶性肿瘤细胞;<span style="color: black;">思虑</span>腺癌;当时看到此报告,我内心是纠结的;这是一个不完善的病理报告,但好在证明了恶性肿瘤,<span style="color: black;">意见</span><span style="color: black;">病人</span>再次取材活检;<span style="color: black;">病人</span>因<span style="color: black;">保持</span>难受拒绝再次活检;只能按肺恶性肿瘤给出治疗<span style="color: black;">方法</span>;当时<span style="color: black;">思虑</span>的治疗<span style="color: black;">方法</span>两种;一种多西他赛+铂;一种培美曲塞二钠+铂化疗;此处我与上级医师治疗上产生了<span style="color: black;">歧义</span>;上级医师认为,<span style="color: black;">病人</span>肺恶性肿瘤诊断<span style="color: black;">知道</span>,但腺癌诊断不<span style="color: black;">知道</span>,<span style="color: black;">意见</span>多西他赛+铂化疗;观察治疗效果;<span style="color: black;">大众</span>懂的,只能按上级<span style="color: black;">大夫</span>的治疗<span style="color: black;">方法</span>执行;<span style="color: black;">病人</span>多西他赛+铂治疗<span style="color: black;">1星期</span>期;<span style="color: black;">时期</span>给予抗感染等治疗;<span style="color: black;">病人</span>肿瘤得到<span style="color: black;">必定</span><span style="color: black;">掌控</span>;阻塞性肺炎较前<span style="color: black;">显著</span><span style="color: black;">掌控</span>;<span style="color: black;">病人</span>症状<span style="color: black;">显著</span>缓解;但肿瘤并未缩小(影像学表现未见肿瘤缩小,当时<span style="color: black;">无</span>留取影像学资料;CT片只能看到阻塞性肺炎吸收;肿瘤未见缩小);在治疗过程中经常和<span style="color: black;">病人</span>及<span style="color: black;">病人</span>家属沟通<span style="color: black;">创立</span>了<span style="color: black;">必定</span>的信任关系,再次<span style="color: black;">意见</span><span style="color: black;">病人</span>取材活检;<span style="color: black;">病人</span>接受<span style="color: black;">意见</span>以后再次取材活检;病理诊断<span style="color: black;">最终</span><span style="color: black;">知道</span>诊断:肺泡型腺癌;立即给<span style="color: black;">病人</span>更换化疗<span style="color: black;">方法</span>;<span style="color: black;">而后</span>给<span style="color: black;">病人</span>抽血做了基因检测(<span style="color: black;">由于</span>气管镜取材组织太少,没办法用组织去做基因检测,<span style="color: black;">否则</span>准确率更高<span style="color: black;">有些</span>,基因检测10基因,<span style="color: black;">好似</span>5000多完全自费;专科<span style="color: black;">大夫</span>一看就<span style="color: black;">晓得</span><span style="color: black;">为何</span>要做这个);给予培美曲塞二钠+铂化疗;化疗后<span style="color: black;">病人</span><span style="color: black;">显著</span>自觉症状好转;再次返院复查胸部CT:如下图</p>
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