两个月治好癌症，120万的CAR-T会做为人类终结癌症的绝招么？
<img src="https://mmbiz.qpic.cn/mmbiz_gif/yZPTcMGWibvsD5PdQWMib8ZmkHdZ1kcSn25uYkG6ksfUTRH25NFyficdDKoiaDB2L57rianoiaZaqrdibwtc5LRU5j0tg/640?wx_fmt=gif&tp=webp&wxfrom=5&wx_lazy=1" style="width: 50%; margin-bottom: 20px;"><p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bw5hH9E5Ohaf0ibfjbYa6MickDgKBKHQ6nsoLZJ8zHESOzibW3Ce4Z6C7Zg/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">近期</span>有个关于癌症治疗的<span style="color: black;">资讯</span>刷屏了：上海一位被确诊淋巴癌的陈阿姨，<span style="color: black;">经过</span> CAR-T 免疫细胞疗法治疗以后，<strong style="color: blue;">仅两个月的时间就痊愈出院。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">并且在<span style="color: black;">大夫</span>的多轮<span style="color: black;">检测</span>下，陈阿姨<span style="color: black;">身体</span><span style="color: black;">已然</span>检测不到癌细胞，肿瘤症状<span style="color: black;">亦</span>完全得到缓解。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bwVkT21g9gG5pCo0fRJAHjhOia0blhXia8grHUonmG1xUbuibtNOqRr8yfg/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;">这件事情可了不得。</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">以往咱们<span style="color: black;">平常</span>的放化疗技术，每次治疗都要忍受<span style="color: black;">剧烈</span>的<span style="color: black;">病痛</span>，<span style="color: black;">重要</span>是几轮化疗下来，癌症还没完全治好，人却被折腾的不行，脱发、食欲不振。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">在经过十几轮的化疗以后，<span style="color: black;">病人</span>可能连伸手拿起筷子<span style="color: black;">摄食</span>的力气都<span style="color: black;">无</span>了，<span style="color: black;">乃至</span>有的<span style="color: black;">病人</span>会<span style="color: black;">选取</span>放弃化疗，只为了能在生命结束前<span style="color: black;">容易</span>的生活。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414q7jCRUicIbopg1rSUKAuZYXbpeFSPjN4hmniaUYPWFxRcfYaRDE3yu6w/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">而这件事的主角<span style="color: black;">便是</span>这个 CAR-T 细胞疗法，这种疗法效果好，<span style="color: black;">况且</span>副<span style="color: black;">功效</span><span style="color: black;">亦</span>小。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bwEDMVca9OoeoQ0ax5dqib44PkcERL0KIncEzP5jbCMibOsBAyvIjQ2dyg/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;">其中的<span style="color: black;">重点</span><span style="color: black;">原由</span>，是<span style="color: black;">由于</span>它能<strong style="color: blue;"><span style="color: black;">经过</span>改造你自己的免疫细胞来杀死你身体里的肿瘤细胞。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">不外</span>这改造免疫细胞可<span style="color: black;">不方便</span>宜。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">一袋装满改造免疫细胞的 65 ml 液体就价值 120 万人民币。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_png/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414rc0Gicj0dNK0Us32luJAyJcacSEfRmPmudBCZsRLeFYrOib9raFFVoHQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">不外</span>， 65ml 、 120 万、治愈癌症这几个字一旦联系起来，网上就<span style="color: black;">显现</span>了<span style="color: black;">各样</span>传闻，<span style="color: black;">例如</span> 120 万打一针就能治好癌症，人类<span style="color: black;">最终</span><span style="color: black;">能够</span>消灭癌症了。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">乃至</span>还有人把 CAR-T 细胞疗法，神话<span style="color: black;">成为了</span><span style="color: black;">能够</span>让人永生的技术。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_png/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414gNJAOuDghDOlRBx7Z3O76yoz2LQbJcW8wrjAExfX5O6btL04sm2myQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">因此</span>差评君就借这个机会跟<span style="color: black;">大众</span>聊一聊这个 CAR-T 细胞疗法，顺便来个谣的辟。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">咱们</span>先下结论：</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">CAR-T 细胞疗法确实是<span style="color: black;">日前</span>治疗癌症最具前景的一项技术，<span style="color: black;">亦</span>的确具备治愈癌症的能力。</span></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_png/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414roFqLk0d3j9CNog6HdaL01icUHL0rpLscIXBJ7AK7wpoCibic1rW7GibmA/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bwDaIz86fQbnTNCSLjnVf1ZFaf9sn4gPmvqvYkOA1iarhoygdiciafhaLaw/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">然则</span>，它不是万能的。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">它的适用范围<span style="color: black;">非常</span>有限，<span style="color: black;">日前</span>仅适用于部分血液肿瘤<span style="color: black;">病人</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">并且能<span style="color: black;">不可</span>用 CAR-T 免疫细胞疗法要经过<span style="color: black;">大夫</span>的多轮<span style="color: black;">评定</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">它<span style="color: black;">亦</span>不是输个液<span style="color: black;">那样</span>简单，前期<span style="color: black;">必须</span>进行<span style="color: black;">繁杂</span>的细胞培养工作，<span style="color: black;">况且</span>很容易失败。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">它之<span style="color: black;">因此</span>值 120 万，是<span style="color: black;">由于</span> CAR-T 细胞疗法是量身定制的，你的液只对你有用。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414BZJs3LWaic0aUFONx0wrJBEzEPMCrl9x0HCK3bnM225AD91MOMsD7OQ/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">那样</span> CAR-T 和<span style="color: black;">咱们</span>之前听的<span style="color: black;">哪些</span>化疗、放疗、靶向治疗<span style="color: black;">乃至</span>干细胞移植疗法又有什么区别呢，有了这技术<span style="color: black;">咱们</span>是不是就<span style="color: black;">不消</span>化疗、放疗了呢？</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bwHvqM3AF57EObumZq4lKkm4QD4NSgich15epyEThkTfXunicfGbAIAyUw/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;">别急，解答你这些疑惑之前，<span style="color: black;">咱们</span>得先<span style="color: black;">认识</span>一下这些疗法的<span style="color: black;">一起</span>的敌人，<strong style="color: blue;">癌细胞。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">癌细胞，就像是<span style="color: black;">一起</span>狗皮膏药，一旦贴你身上，就很难扯下来。<strong style="color: blue;">你要是想来硬的，那就得做好掉层皮的准备。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_gif/yZPTcMGWibvte4Sia49SrDm9sibDCJS24149YoYMmXP9FSHMkAdQMsh7A1F055LI86ernGqbBwytIAHbzz8AoibDGQ/640?wx_fmt=gif&tp=webp&wxfrom=5&wx_lazy=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">它<span style="color: black;">善于</span>伪装<span style="color: black;">，能够<span style="color: black;">容易</span>骗过免疫细胞的排查。</span></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">还能虚弱<span style="color: black;">免疫细胞，减缓免疫细胞的查杀速度，并且削弱它的杀伤力。</span></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">乃至</span>在被免疫细胞<span style="color: black;">发掘</span>时，它还会劫持正常的细胞给自己当人质，<span style="color: black;">乃至</span><span style="color: black;">能够</span>远程爆破免疫细胞，直接将其杀死。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414j9rAh1oKY0VOohpka5qsQspAB7EsRzbHR6BALdDxpYyknaY6MaoiaLQ/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bwSpBMfELaANrYkGZgaVZgx7SpPFyFoMxTCcxCicnOs549yP6Xfg4aKicw/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">由于</span>这些特殊技能，癌细胞能在身体里肆意妄为，正常的免疫系统压根杀不死它们</span><strong style="color: blue;">，<span style="color: black;">因此</span>癌症的复发率很高。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;"><span style="color: black;">倘若</span>放任不管，等到癌细胞把免疫细胞杀光的那一刻，生命<span style="color: black;">亦</span>就结束了，</span><strong style="color: blue;"><span style="color: black;">因此</span>癌症的致死率<span style="color: black;">亦</span>很高。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_png/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414FrmXJZUENfkl0V3PYA1FKbyq5M8GicNaw9BChXKAZv8kJ7Y7zYEBdXA/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">而<span style="color: black;">咱们</span>传统的化疗、放疗、靶向治疗和造血干细胞移植等疗法，都是些杀敌一千自损八百的治法。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bwUUK9k2aNq5gMlsqZ6u94vm3tJ882ycjE4g0axZ6UzIHiaAFibvortJ7Q/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;">它们在杀死癌细胞的<span style="color: black;">同期</span>，<span style="color: black;">亦</span>会不可避免的误杀到正常细胞。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">例如</span>化疗会<span style="color: black;">导致</span>癌症<span style="color: black;">病人</span>的脱发，放疗会<span style="color: black;">导致</span>正常身体组织的<span style="color: black;">损害</span>，并且还会产生放射性的炎症，靶向治疗则有可能带来心血管系统、<span style="color: black;">呼气</span>系统<span style="color: black;">乃至</span>神经系统的并发症。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414B489l9Ou50iaCnuv90LJvicL0XrMXSFTCiahBnavnBPmfvYxpro6aBw8w/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">相较于上面<span style="color: black;">哪些</span>传统<span style="color: black;">办法</span>，<span style="color: black;">日前</span><span style="color: black;">害处</span>最小的造血干细胞移植疗法，虽然能最大限度的杀死癌细胞，还会<span style="color: black;">守护</span>人体正常的造血功能，<span style="color: black;">然则</span>却<span style="color: black;">必须</span>进行<span style="color: black;">长时间</span>的抗排异治疗，并且<span style="color: black;">亦</span>仅适用于某些高度恶性淋巴瘤，范围有限。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">而和上面所有手段相比， CAR-T 细胞疗法的<span style="color: black;">优良</span><span style="color: black;">亦</span>就<span style="color: black;">表现</span>了出来。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414RtG1h8r2R8MT6xEibcckHVricbWNq61ShNqHxD4HiabYDVzIoiciciaciaUdw/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bwAUYx6icr5qlsVGlZFOnJIoiaTUyMJtKB4kBwicd2uC60n6vQW4kZIRezw/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;">它<span style="color: black;">经过</span>基因工程技术对免疫 T 细胞进行改造，<span style="color: black;">经过</span>分析<span style="color: black;">病人</span>肿瘤细胞的特性，<strong style="color: blue;"><span style="color: black;">研发</span>出一种能够嵌合在 T 细胞上的武器。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">改造后的 T 细胞<span style="color: black;">便是</span> CAR-T 细胞。<span style="color: black;">由于</span>武器的存在，这种细胞不仅能更快更准更深入地识别癌细胞，还能在癌细胞采取<span style="color: black;">办法</span>之前，就把它秒杀掉。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">当然，在注射</span>之前，<span style="color: black;">病人</span>还要接受适当的化疗，尽可能的减小<span style="color: black;">身体</span>的肿瘤细胞数量，尽可能<span style="color: black;">加强</span> T 细胞的胜算。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">不外</span> CAR-T <span style="color: black;">亦</span>不是完全<span style="color: black;">无</span>副<span style="color: black;">功效</span>。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">首要</span>，它会<span style="color: black;">引起</span>细胞因子风暴。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_png/yZPTcMGWibvte4Sia49SrDm9sibDCJS24142sQHWGNbWnVWPHu0gibwIjTibngm3F1WQE2UQs5NTwUico6c5K4mbwbDg/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">海量</span> CAR-T 进入身体后，你的身体就<span style="color: black;">成为了</span>刺激战场，有癌细胞的<span style="color: black;">地区</span>就有枪战，这可能会给<span style="color: black;">病人</span>带来<span style="color: black;">连续</span><span style="color: black;">持续</span>的高烧，腹泻等症状，严重时还可能会危及生命。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">除此之外，<span style="color: black;">便是</span>可能<span style="color: black;">导致</span>神经毒性副<span style="color: black;">功效</span>，<span style="color: black;">例如</span>神经错乱、丧失语言能力、诱发癫痫等危险，<span style="color: black;">不外</span><span style="color: black;">日前</span>还不清楚产生这一副<span style="color: black;">功效</span>的基本机制。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414UicyI5BRsp2uaHT3p6hBnibv1BOK1KaNT7yvtU2xIL0lRfjG5UPoz3yw/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bwyhCOB1ibZrF8yfH9aqwSlmKNN9HPCnANH961scibicUKYIZI7dLV4oZhg/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;">尽管有副<span style="color: black;">功效</span>，但这个技术的效果真的非常牛逼。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">按照</span>美国 Kite Pharma <span style="color: black;">颁布</span>的临床<span style="color: black;">实验</span>数据，<span style="color: black;">经过</span>随访 101 名经过 CAR-T 免疫细胞疗法的淋巴癌<span style="color: black;">病人</span>，<strong style="color: blue;">它们一年内的总缓解率达到 83% ，完全缓解率 58% ，在以往的治疗手段里，化疗的总缓解率仅有 41%。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">并且<span style="color: black;">她们</span>在接受 CAR-T 细胞免疫疗法以后，都进行了有效的防护和监控，<span style="color: black;">因此</span>并<span style="color: black;">无</span><span style="color: black;">显现</span>因副<span style="color: black;">功效</span>死亡的病例。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">不外</span>癌症<span style="color: black;">病人</span>最看重的可不只是这一时<span style="color: black;">或</span>一年的治疗效果，最<span style="color: black;">要紧</span>的还是不要复发。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bw7A5QXcuCMd6hpEbo5lFicuMHicSCPiberT1LDttgV4oqazQcsnp908BiaQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">因此</span> CAR-T 依然还<span style="color: black;">必须</span>更长的时间来检验。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414pr8LrjQHXmdzyhZO7aANjOeEHXu7DuCawm4RI6iaKYSc4RyNEch2gAA/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">全世界</span><span style="color: black;">第1</span>个接受 CAR-T 细胞免疫疗法的<span style="color: black;">病人</span>， Emily Whitehead ，它在 2012 年接受治疗，之后连续六年癌症未复发，<span style="color: black;">因此呢</span>当选了 2017 年 Nature 杂志封面<span style="color: black;">名人</span>，今年<span style="color: black;">亦</span>迎来了<span style="color: black;">没</span>癌<span style="color: black;">存活</span>的第九年。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">美国是<span style="color: black;">全世界</span>首个<span style="color: black;">准许</span> CAR-T 免疫疗法的国家，当年的定价<span style="color: black;">亦</span><span style="color: black;">非常</span><span style="color: black;">昂贵</span>，起步价 40 万美元，折合人民币 200 多万，<span style="color: black;">此刻</span>的价格依然稳定在 37-47 万美元之间。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414CUg9REh1icSnV4iaslwN7uVNXBs8e4sZU6cnoiaYfPwTHYUdPGvFTvylw/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">国内这边，今年的 6 月 22 日，复星凯特生物科技有限<span style="color: black;">机构</span>的阿基仑赛注射液，<span style="color: black;">作为</span>了中国首款<span style="color: black;">获准</span>上市的 CAR-T 细胞治疗<span style="color: black;">制品</span>，开头<span style="color: black;">说到</span>的陈阿姨<span style="color: black;">亦</span>是国内首例接受 CAR-T 细胞免疫疗法并成功痊愈出院的<span style="color: black;">病人</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><img src="https://mmbiz.qpic.cn/mmbiz/yZPTcMGWibvvLx6F9VHHuduYRiaYhaE4bwbRzDYYu9iasx9mUuEb4ZzyIvohic9iaYYIiag545E5fsNE2WSlr8yZIjiag/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">因此</span>说， CAR-T 免疫疗法，<span style="color: black;">亦</span>算是弥补了中国抗癌<span style="color: black;">行业</span>的最后<span style="color: black;">一起</span>拼图。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414xgWIROQpBb5iaUoEpCSetLRDkWiaRLnh5hP1zcl9JKdQunCYK6r3YkGg/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">虽然它<span style="color: black;">日前</span>只能用来治疗部分血液肿瘤，<span style="color: black;">然则</span>一旦<span style="color: black;">把握</span>了给免疫 T 细胞加装备的技术，<span style="color: black;">咱们</span>就<span style="color: black;">能够</span>针对不同的肿瘤给 T 细胞加上不同的 CAR ，<span style="color: black;">将来</span>它将会被用来治愈<span style="color: black;">更加多</span>类型的肿瘤。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">说在最后，之前知乎上有个关于 CAR-T 的的一个问题，问题是：<span style="color: black;">怎样</span>看待国内首例 CAR-T </strong><strong style="color: blue;">治疗<span style="color: black;">病人</span><span style="color: black;">恢复</span>出院，</strong><strong style="color: blue;">120 万治疗癌症值不值</strong><strong style="color: blue;">？</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_png/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414mRVZIIMSahria4aM88J65nGjd3e7A5WlGwp9oycxcjth8UyKpJr8YCg/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">差评君觉得，压垮癌症<span style="color: black;">病人</span>的最后一根稻草可能不是有<span style="color: black;">无</span>这 120 万买包药，而是能<span style="color: black;">不可</span>给<span style="color: black;">她们</span>一个对抗病魔的决心和一个<span style="color: black;">保持</span>活下去的<span style="color: black;">期盼</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">撰写：</span></strong><span style="color: black;">yx <strong style="color: blue;">编辑：</strong>面线</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;"><span style="color: black;">照片</span>、参考资料<span style="color: black;">源自</span>：</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">WIKIPEDIA — Cy to k i n e r el e ase syn d r ome </span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">WIKIPEDIA —C h i m e ric a ntig e n r ecept o r T c e ll</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">知乎 - <span style="color: black;">怎样</span>看待国内首例 CAR-T 治疗<span style="color: black;">病人</span><span style="color: black;">恢复</span>出院， 120 万治疗癌症值不值？</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">Nature-EMILY WHITEHEAD : Living testimonial </span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">知乎 - 咚咚肿瘤科</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">腾讯医典— CAR-T 是什么</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">医学百科 -CAR-T</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">百度 - 血液肿瘤；实体肿瘤；靶向治疗；造血干细胞<span style="color: black;">始终</span>；白血病；</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">Google- 癌症；发烧</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/yZPTcMGWibvte4Sia49SrDm9sibDCJS2414luc2L3VszIicDuDM2d9NkcIhWz8ADXdCyr3lz89ckDzdu4EFpf7IjfQ/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></p>
我深感你的理解与共鸣，愿对话长流。
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