tw4ld6 发表于 2024-6-23 18:28:52

骨髓炎的临床表现及中医调治


    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">在急性血源性骨髓炎,全身症状严重。前躯症状有全身倦怠,继以全身酸痛,食欲不振,畏寒,严重者可有寒战,多有驰张性高热达39~41℃,烦燥不安,脉搏快弱,<span style="color: black;">乃至</span>有谵妄,<span style="color: black;">晕倒</span>等败血症现象,<span style="color: black;">也</span>可<span style="color: black;">显现</span>脑膜刺激症状。此病人<span style="color: black;">常常</span>有贫血脱水和酸中毒。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(一)发病年龄与部位</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">急性血源性化脓性骨髓炎可<span style="color: black;">出现</span>在任何年龄,但以学龄儿童及青少年为多见,新生儿<span style="color: black;">也</span>可<span style="color: black;">出现</span>。男孩较多,可能<span style="color: black;">因为</span>活动多易受外伤<span style="color: black;">导致</span>。以胫骨及股骨为最多,其次为肱骨。外伤性骨髓炎则因外伤<span style="color: black;">状况</span>可<span style="color: black;">出现</span>于任何年龄及部位,战伤中多见。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(二)症状</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">1.全身症状 在急性血源性骨髓炎,全身症状严重。前躯症状有全身倦怠,继以全身酸痛,食欲不振,畏寒,严重者可有寒战,多有驰张性高热达39~41℃,烦燥不安,脉搏快弱,<span style="color: black;">乃至</span>有谵妄,<span style="color: black;">晕倒</span>等败血症现象,<span style="color: black;">也</span>可<span style="color: black;">显现</span>脑膜刺激症状。此病人<span style="color: black;">常常</span>有贫血脱水和酸中毒。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">外伤后<span style="color: black;">导致</span>的急性骨髓炎,除非有严重并发症或<span style="color: black;">海量</span>软组织<span style="color: black;">损害</span>及感染等,<span style="color: black;">通常</span>全身症状较轻,感染多较局限而少<span style="color: black;">出现</span>败血症,但应<span style="color: black;">重视</span>并发厌气菌感染的危险。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">2.局部症状 血源性骨髓炎<span style="color: black;">初期</span>有局部剧烈<span style="color: black;">病痛</span>和跳痛,肌肉有<span style="color: black;">守护</span>性痉挛,肢体不敢活动。患部肿胀及压痛<span style="color: black;">显著</span>。如病灶接近关节,则关节<span style="color: black;">也</span>可肿胀,但压痛不<span style="color: black;">明显</span>。当脓肿穿破骨质、骨膜至皮下时,即有波动,穿破皮肤后,形成窦道,经久不愈。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">在外伤性骨髓炎,有开放骨折及软组织<span style="color: black;">损害</span>等,<span style="color: black;">按照</span>局部<span style="color: black;">损害</span>程度,感染范围而有不同表现。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(三)X线<span style="color: black;">检测</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">急性血源性骨髓炎早期<span style="color: black;">没</span><span style="color: black;">显著</span>变化,发病后3周<span style="color: black;">上下</span>可有骨质脱钙、破坏,少量骨膜增生,以及软组织肿胀<span style="color: black;">暗影</span>等。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(四)化验<span style="color: black;">检测</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">在急性血源性骨髓炎,<span style="color: black;">初期</span>血培养阳性率较高,局部脓液培养有化脓性细菌,应作细菌培养及<span style="color: black;">药品</span><span style="color: black;">敏锐</span><span style="color: black;">实验</span>,以便<span style="color: black;">即时</span><span style="color: black;">选择</span>有效<span style="color: black;">药品</span>。血化验中白血球及中性多核白血球均<span style="color: black;">升高</span>,<span style="color: black;">通常</span>有贫血。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">应尽早诊断血源性骨髓炎,以便<span style="color: black;">即时</span>治疗。<span style="color: black;">初期</span>诊断<span style="color: black;">重点</span><span style="color: black;">按照</span>临床表现和血培养;如有局部蜂窝组织炎表现,应<span style="color: black;">思虑</span>有骨髓炎并给适当抗菌<span style="color: black;">药品</span>等治疗,必要时,局部穿刺抽取脓液作细菌培养。外伤所<span style="color: black;">导致</span>骨髓炎,<span style="color: black;">按照</span>外伤病史及局部症状<span style="color: black;">就可</span>诊断。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">急性血源性骨髓炎应与下列疾患鉴别:</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">1.蜂窝组织炎,全身中毒症状较轻,局部炎症较广泛,压痛范围<span style="color: black;">亦</span><span style="color: black;">很强</span>。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">2.急性化脓性关节炎,肿胀、压痛在关节间隙而不在骨端,关节动度几乎完全消失,有疑问时,关节腔穿刺抽液<span style="color: black;">检测</span>可<span style="color: black;">知道</span>诊断。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">3.风湿性关节炎,<span style="color: black;">通常</span>病情较轻,发热较低,局部症状<span style="color: black;">也</span>较轻,病变部位在关节,且常有多个关节受累。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/UGAb2H64KzcGvBpPwR2wtUsWzPmzweCibFO8biczGfoBk2ay6aO5E83fQj1ibxLSwTPtFicYg9580oM9clOOtdhPYA/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">慢性骨髓炎是<span style="color: black;">出现</span>于骨组织的慢性感染,病变可<span style="color: black;">触及</span>骨髓、骨质、骨膜及<span style="color: black;">周边</span>软组织,<span style="color: black;">导致</span>骨髓破坏、骨质坏死、骨膜穿破、皮肤破溃,形成一个或多个瘘 管、窦道、反复排出脓汁或死骨,瘘口<span style="color: black;">周边</span>,皮肤色素沉着及瘢痕形成。<span style="color: black;">倘若</span>皮肤表面愈合,而内有脓液排除不畅或遇外伤寒冷及抵抗力下降,局部肿胀、<span style="color: black;">病痛</span>加剧,<span style="color: black;">显现</span>发热和全身不适的症状。之后,再次破溃、流脓,经久不愈,致使局部肌肉萎缩、全身消瘦、神疲<span style="color: black;">没</span>力、食欲<span style="color: black;">衰退</span>、腰膝<span style="color: black;">疲软</span>等症状,慢性骨髓炎骨质破坏严重,可并发病理性骨折、肢体畸形、关节强直、癌变等并发症。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/UGAb2H64KzcGvBpPwR2wtUsWzPmzweCibH6elMsyzUftywtIicmkog6ibnfHuVzxaalcWqmgLlbwxaekNTT1PrYMQ/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">慢性骨髓炎多由急性骨髓炎治疗不<span style="color: black;">即时</span>或不彻底转变而来。中医认为骨髓炎是附着于骨的深部脓疡。急性骨髓炎叫附骨痈,慢性骨髓炎叫附骨疽。发病<span style="color: black;">原由</span>有内因和外因两种<span style="color: black;">原因</span>。内因是身体虚弱、抵抗力下降;外因或为热病后热毒未尽,深蕴入内流注于骨繁衍聚毒为病;或为金刃所伤、邪毒侵延注骨为病;或为筋伤后淤血化热、深蕴入里、留于筋骨、经络阻隔、气凝血滞、腐筋蚀骨、蕴郁成脓、破溃而出。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/UGAb2H64KzcGvBpPwR2wtUsWzPmzweCibGib6cT07CsEWKBDedfVDwdS6ArWD8uic2j5JiaPm5DYpov8fPicboMibaEg/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">慢性骨髓炎的治疗要充分<span style="color: black;">表现</span>内外兼治的原则。内应扶养正气、<span style="color: black;">加强</span>机体抵抗力,<span style="color: black;">加强</span>机体对外来邪毒的抗病能力。<span style="color: black;">重点</span>采用养阴益气、温肾健脾、托里排毒等<span style="color: black;">办法</span>,这是治疗的<span style="color: black;">重要</span>。它不仅<span style="color: black;">能够</span>促进脓液、死骨的排出,窦道的<span style="color: black;">早点</span>愈合,还<span style="color: black;">能够</span>防止窦道的反复<span style="color: black;">爆发</span>。外治要从三步进行:一要排毒,用<span style="color: black;">拥有</span>排脓、腐蚀<span style="color: black;">功效</span>的中药,自内而外破坏窦道和死骨,促进脓液、死骨和<span style="color: black;">没</span>活力组织排出,使肉芽鲜红形成<span style="color: black;">鲜嫩</span>创面。二要生肌,采用<span style="color: black;">拥有</span>祛腐生肌、长肉敛疮<span style="color: black;">功效</span>的中药,自内向外促进骨髓、骨质、肌肉及皮肤组织再生和修复,最后使窦口愈合。三对大块死骨及病灶<span style="color: black;">没</span>法排出时,可采用手术<span style="color: black;">办法</span>进行病灶清理、死骨清除、连续灌洗术。对皮肤、软组织<span style="color: black;">缺失</span>严重,创面深陷呈漏斗状者应行带蒂肌瓣填充术,方能消灭死腔。</p>
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