骨髓增生反常综合症的症状有哪些
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="http://mmbiz.qpic.cn/mmbiz_gif/InOictSWj0GyTIAEgic7ZzGsBgPt7LXAIgJd59hd4rVN31c4UVrGKoJCZBBZAsfIvEnU0De1PIibeyj3CicJ9NZ4XA/0?wx_fmt=gif&tp=webp&wxfrom=5&wx_lazy=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">血液病专家<span style="color: black;">暗示</span><span style="color: black;">非常多</span>人都不是很清楚骨髓增生<span style="color: black;">反常</span><span style="color: black;">综合症</span>(mds)是什么<span style="color: black;">疾患</span>,骨髓增生<span style="color: black;">反常</span><span style="color: black;">综合症</span>的症状有<span style="color: black;">那些</span>?<span style="color: black;">倘若</span>不清楚症状<span style="color: black;">没</span>法确诊就<span style="color: black;">没</span>法<span style="color: black;">即时</span>的进行治疗,从而使<span style="color: black;">生病</span>的<span style="color: black;">病人</span>及<span style="color: black;">病人</span>家属都造<span style="color: black;">成为了</span>很大的<span style="color: black;">害处</span>。其实人们能很好的<span style="color: black;">认识</span>骨髓增生<span style="color: black;">反常</span><span style="color: black;">综合症</span>的<span style="color: black;">关联</span>症 状,<span style="color: black;">病人</span>能得到<span style="color: black;">即时</span>的治疗。<span style="color: black;">因此</span><span style="color: black;">认识</span>骨髓增<span style="color: black;">反常</span><span style="color: black;">综合症</span>的症状是很<span style="color: black;">要紧</span>的,下面将由血液病专家给<span style="color: black;">大众</span>进行讲解,<span style="color: black;">期盼</span>能<span style="color: black;">帮忙</span>到<span style="color: black;">大众</span>。</p>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">骨髓增生<span style="color: black;">反常</span>综合症的<span style="color: black;">详细</span>内容</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">临床上大多表现为全细胞减少,骨髓造血细胞增生<span style="color: black;">升高</span>伴病态造血。<span style="color: black;">都数</span>学者认为发病<span style="color: black;">原由</span>系因化学<span style="color: black;">药品</span>、化学物质以及放射性物质<span style="color: black;">引起</span>造血干细胞<span style="color: black;">反常</span>增殖、分化而发病。该病分为难治性贫血(ra)、难治性贫血伴环形铁粒幼细胞<span style="color: black;">增加</span>(ras)、难治性贫血伴原始细胞<span style="color: black;">增加</span>(raeb)、转变中的难治性贫血伴原努 细胞<span style="color: black;">增加</span>(raeb-t)、慢性粒单核细胞白血病(cmml)五个类型(who将慢性粒单核细胞白血病归类到骨髓增殖性<span style="color: black;">疾患</span>,转变中的难治性贫血伴原始细胞<span style="color: black;">增加</span>归类到急性白血病)。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"> <strong style="color: blue;"><span style="color: black;">第<span style="color: black;">1、</span>贫血为主</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">大<span style="color: black;">都数</span>有症状的<span style="color: black;">病人</span><span style="color: black;">常常</span>主诉<span style="color: black;">逐步</span><span style="color: black;">出现</span>疲倦、乏力、气短和面色苍白、口唇指甲苍白、<span style="color: black;">乃至</span><span style="color: black;">头昏</span>、心悸、发热、鼻腔、牙龈<span style="color: black;">流血</span>,约20%<span style="color: black;">病人</span>脾脏肿大,但半 数<span style="color: black;">病人</span><span style="color: black;">没</span>症状,在体检或偶然<span style="color: black;">发掘</span>。实验室<span style="color: black;">检测</span>,血常规<span style="color: black;">检测</span>表现为贫血、红细胞、血红蛋白减少者占90%,半数<span style="color: black;">病人</span>红细胞、白细胞、血小板均减少,<span style="color: black;">亦</span>有<span style="color: black;">少许</span> 单纯血小板减少,且见巨大红细胞、巨大血小板、有核红细胞等病态造血,骨髓增生正常或活跃或<span style="color: black;">显著</span>活跃者占95%,仅小数<span style="color: black;">病人</span>增生减低,均伴有病态造血,铁 染色高于正常值</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"> <span style="color: black;"><strong style="color: blue;"> <span style="color: black;">第<span style="color: black;">2、</span>骨髓增生<span style="color: black;">反常</span>综合症的症状</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">mds临床表现<span style="color: black;">没</span>特殊性,mds<span style="color: black;">一般</span>起病缓慢,<span style="color: black;">少许</span>起病急剧。<span style="color: black;">通常</span>从发病<span style="color: black;">起始</span>转化为白血病,在一年之内约由50%以上。贫血<span style="color: black;">病人</span>占90%。<span style="color: black;">包含</span>面色苍 白、乏力、活动后心悸、气短,老年人贫血常使原有的慢性心、肺<span style="color: black;">疾患</span>加重。发热占50%,其中<span style="color: black;">原由</span>不明性发热占10%~15%,表现为反复<span style="color: black;">出现</span>的感染及发热,感染部位以<span style="color: black;">呼气</span>道,肛门<span style="color: black;">周边</span>和泌尿系为多。严重的粒细胞缺乏可降低<span style="color: black;">病人</span>的抵抗力。<span style="color: black;">流血</span>占20%,<span style="color: black;">平常</span>于<span style="color: black;">呼气</span>道,消化道,<span style="color: black;">亦</span>由颅内<span style="color: black;">流血</span>者,<span style="color: black;">初期</span>的<span style="color: black;">流血</span>症 状较轻,多为皮肤粘膜<span style="color: black;">流血</span>,牙龈出血或鼻衄,女性<span style="color: black;">病人</span>可有<span style="color: black;">大姨妈</span><span style="color: black;">太多</span>。晚期<span style="color: black;">流血</span>趋势加重,脑<span style="color: black;">流血</span><span style="color: black;">作为</span><span style="color: black;">病人</span>死亡的<span style="color: black;">重点</span><span style="color: black;">原由</span>之一。严重的血小板降低可致皮肤淤斑、鼻<span style="color: black;">流血</span>、牙龈<span style="color: black;">流血</span>及内脏<span style="color: black;">流血</span>。<span style="color: black;">少许</span><span style="color: black;">病人</span>可<span style="color: black;">相关</span>节肿痛,发热、皮肤血管炎等症状,多伴有 <span style="color: black;">自己</span>抗体,类似风湿病。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"> <span style="color: black;"><strong style="color: blue;"><span style="color: black;">第<span style="color: black;">3、</span>骨髓增生<span style="color: black;">反常</span>综合症的体征</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">mds<span style="color: black;">病人</span>体征不典型。常为贫血<span style="color: black;">导致</span>面色苍白,血小板减少<span style="color: black;">导致</span>皮肤淤点、淤斑。肝脾肿大者约占10%<span style="color: black;">上下</span>。极<span style="color: black;">少许</span><span style="color: black;">病人</span>可有淋巴结肿大和皮肤浸润,多为慢性粒单核细胞白血病(cmmol)型<span style="color: black;">病人</span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"> <span style="color: black;"><strong style="color: blue;"> <span style="color: black;">第<span style="color: black;">4、</span>特殊类型临床表现</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">5q-<span style="color: black;">综合症</span>:骨髓增生<span style="color: black;">反常</span>综合症<span style="color: black;">病人</span>第5号染色体长臂缺失而不伴有其他染色体畸变。多<span style="color: black;">出现</span>在老年女性,临床表现为难治性巨细胞贫血,除偶需输血外临床病情长期稳定,很少转变为急性白血病。50%<span style="color: black;">病人</span>可有脾大,血小板正常或偶尔<span style="color: black;">增多</span>,骨髓中最<span style="color: black;">明显</span>的表现为有低分叶或<span style="color: black;">没</span>分叶的巨核细胞,常合并中等程度病态造血,但粒系造血正常。</p> <span style="color: black;"><strong style="color: blue;">温馨提示:</strong></span>对上文中的介绍<span style="color: black;">期盼</span><span style="color: black;">大众</span>能够<span style="color: black;">即时</span>的去<span style="color: black;">认识</span>清楚,<span style="color: black;">倘若</span>家里有人<span style="color: black;">身患</span>血液<span style="color: black;">疾患</span>,不妨到我院试一试,我院有首席专家学者致力于血液病减轻<span style="color: black;">病人</span>的痛苦,正规的治疗在这个寒冷的冬天<span style="color: black;">保准</span><span style="color: black;">病人</span>的健康。<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="http://mmbiz.qpic.cn/mmbiz_gif/InOictSWj0GyTIAEgic7ZzGsBgPt7LXAIgX0nuz5t0z2UItMH3miaT0rpxaS5JtrXtfIKpLLnlxMJpwwwYSgouibGg/0?wx_fmt=gif&tp=webp&wxfrom=5&wx_lazy=1" style="width: 50%; margin-bottom: 20px;"></p>
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