莫要慌,肿瘤标志物加强不必定便是癌
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">体检报告出来,哪一项超标了你最紧张?尿酸?血脂?还是心电图、<span style="color: black;">彩超</span><span style="color: black;">反常</span>?除了这些,再淡定的人看到这一项<span style="color: black;">反常</span>了估计心里都要吓一跳,它<span style="color: black;">便是</span>肿瘤标志物!好多人看到肿瘤就想到癌,可能觉得这项都超标了,那肯定多半是得癌症了,可怎么办哦! !!新桥医院胸外科<span style="color: black;">专家</span>戴纪刚提示<span style="color: black;">大众</span>,肿瘤标志物即使检测出来超标<span style="color: black;">亦</span>不要太过惊慌,<span style="color: black;">由于</span>它<span style="color: black;">上升</span>了不<span style="color: black;">必定</span><span style="color: black;">便是</span>癌症!</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">什么是肿瘤标志物?</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">肿瘤标志物<span style="color: black;">重点</span><span style="color: black;">指的是</span>反映了肿瘤<span style="color: black;">是不是</span>存在的一类化学物质。肿瘤标志物分为<span style="color: black;">非常多</span>种,有的只存在于胚胎组织而不存在于成年个体中;有的在肿瘤<span style="color: black;">病人</span><span style="color: black;">身体</span>含量远超于正<span style="color: black;">一般人</span>,它的存在或是含量的改变<span style="color: black;">能够</span>提示肿瘤的性质,从而<span style="color: black;">帮忙</span><span style="color: black;">大夫</span><span style="color: black;">认识</span>肿瘤的<span style="color: black;">出现</span>及细胞功能,从而对肿瘤的诊断、<span style="color: black;">归类</span>、预后判断和治疗<span style="color: black;">供给</span><span style="color: black;">必定</span>的<span style="color: black;">指点</span><span style="color: black;">帮忙</span>。肿瘤标志物检测是<span style="color: black;">初期</span><span style="color: black;">发掘</span><span style="color: black;">没</span>症状微灶肿瘤的途径之一,外周血,尿液、胸腹水、组织细胞等都<span style="color: black;">能够</span>检测肿瘤标志物。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">“理想”的肿瘤标志物<span style="color: black;">通常</span>认为应<span style="color: black;">拥有</span>下列特点:(1)<span style="color: black;">敏锐</span>性高,能在<span style="color: black;">初期</span>就检测出长了肿瘤的<span style="color: black;">病人</span>;(⑵)特异性好,能准确鉴别肿瘤<span style="color: black;">病人</span>和其它<span style="color: black;">疾患</span><span style="color: black;">病人</span>;(3)能对肿瘤定位;(4)血清中标志物的浓度与瘤体<span style="color: black;">体积</span>、临床分期<span style="color: black;">关联</span>,<span style="color: black;">能够</span><span style="color: black;">帮忙</span><span style="color: black;">大夫</span>判断<span style="color: black;">病人</span>的<span style="color: black;">详细</span>预后;(5)半衰期短,能反映肿瘤的动态变化;(6)测定<span style="color: black;">办法</span><span style="color: black;">精细</span>度高、准确性好,操作简便,价格便宜。但<span style="color: black;">迄今</span>为止,<span style="color: black;">因为</span>肿瘤基因<span style="color: black;">非常</span><span style="color: black;">繁杂</span>,<span style="color: black;">无</span>一种肿瘤是单一类型的,故<span style="color: black;">发掘</span>“理想”的肿瘤标志物就<span style="color: black;">非常</span>困难。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">为何</span>正<span style="color: black;">一般人</span>的肿瘤标志物水平<span style="color: black;">亦</span>会<span style="color: black;">上升</span>?</p><span style="color: black;">通常</span><span style="color: black;">来讲</span>,恶性肿瘤<span style="color: black;">病人</span><span style="color: black;">通常</span>肿瘤标志物的含量会有<span style="color: black;">明显</span><span style="color: black;">升高</span>。<span style="color: black;">然则</span>不是所有的恶性肿瘤都会<span style="color: black;">导致</span>肿瘤标志物的<span style="color: black;">上升</span>,这要<span style="color: black;">按照</span>肿瘤标志物的特异性与灵敏度来决定。正<span style="color: black;">一般人</span>在体检过程中<span style="color: black;">发掘</span>肿瘤标志物水平<span style="color: black;">上升</span>的<span style="color: black;">平常</span><span style="color: black;">原由</span>如下:
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(1) 人群差异</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">虽然肿瘤标志物<span style="color: black;">大都是</span>由肿瘤产生的物质,但有<span style="color: black;">有些</span>肿瘤标志物在正常组织或良性病变中<span style="color: black;">一样</span><span style="color: black;">能够</span>产生,但这类人群所占的比例较低且存在个体差异。这类人群<span style="color: black;">一样</span>要<span style="color: black;">注意</span>肿瘤标志物,其数值的<span style="color: black;">增多</span>可能是炎症<span style="color: black;">或</span>是癌细胞的轻度<span style="color: black;">增多</span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(2)样品存储问题</p>血液标本<span style="color: black;">倘若</span>储存<span style="color: black;">欠妥</span><span style="color: black;">亦</span>会<span style="color: black;">引起</span>肿瘤标志物的指标<span style="color: black;">上升</span>。如容器、抗凝剂、<span style="color: black;">保留</span>液及储藏等<span style="color: black;">显现</span>问题,会<span style="color: black;">引起</span>样品<span style="color: black;">不可</span>准确反映<span style="color: black;">病人</span>的<span style="color: black;">实质</span><span style="color: black;">状况</span>。
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(3)<span style="color: black;">药品</span>使用</p>如胸腺肽、狂犬疫苗等生物制剂的<span style="color: black;">运用</span>后,有可能<span style="color: black;">导致</span>某些肿瘤标志物指标的<span style="color: black;">上升</span>。布洛芬、类固醇、奥美拉唑等<span style="color: black;">药品</span>以及某些保健品和中药<span style="color: black;">亦</span>会<span style="color: black;">引起</span>部分人群肿瘤标志物<span style="color: black;">反常</span>。例如消化道肿瘤标志物CA724是一种糖类抗原,<span style="color: black;">倘若</span><span style="color: black;">病人</span><span style="color: black;">吃下</span>了灵芝等含有多糖物质的保健品,其血清CA724浓度会大幅<span style="color: black;">上升</span>,停药后<span style="color: black;">就可</span>降至正常。
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(4)特殊<span style="color: black;">状况</span></p>饮酒、吸烟、<span style="color: black;">睡觉</span><span style="color: black;">不良</span>、局部炎症、血糖<span style="color: black;">掌控</span><span style="color: black;">不良</span>,过度进补等都会影响<span style="color: black;">检测</span>结果。<span style="color: black;">例如</span>糖尿病会<span style="color: black;">增多</span>癌症的<span style="color: black;">出现</span><span style="color: black;">危害</span>,血糖<span style="color: black;">掌控</span>差的糖尿病<span style="color: black;">病人</span><span style="color: black;">亦</span>会<span style="color: black;">显现</span>CA199、CEA等肿瘤标志物<span style="color: black;">上升</span>。<span style="color: black;">另外</span>,<span style="color: black;">科研</span><span style="color: black;">表示</span>,<span style="color: black;">长时间</span><span style="color: black;">摄食</span>燕窝<span style="color: black;">这般</span>的补品容易刺激细胞过度分化,影响肿瘤标志物的<span style="color: black;">上升</span>。<span style="color: black;">针对</span>女性<span style="color: black;">来讲</span>,<span style="color: black;">处在</span>怀孕期或<span style="color: black;">大姨妈</span>期时前后抽血,都会因个人身体差异产生波动。<span style="color: black;">倘若</span>体检<span style="color: black;">发掘</span>肿瘤标志物<span style="color: black;">上升</span>,先回忆一下,<span style="color: black;">近期</span><span style="color: black;">是不是</span>存在这些应激<span style="color: black;">原因</span>。
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">发掘</span>肿瘤标志物<span style="color: black;">上升</span>怎么办?</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">首要</span>要做的是放松心情!不要胡思乱想自己把自己吓到了!<span style="color: black;">而后</span>再去正规医院寻求专业的<span style="color: black;">帮忙</span>,<span style="color: black;">大夫</span>会结合你近段时间的身体<span style="color: black;">情况</span>,以及X光、<span style="color: black;">彩超</span>、CT、MRI、胃镜、肠镜等影像学<span style="color: black;">检测</span>手段综合判断。就像前面<span style="color: black;">说到</span>的,在肿瘤标志物检测中<span style="color: black;">导致</span>假阳性的<span style="color: black;">原因</span><span style="color: black;">非常多</span>,<span style="color: black;">例如</span><span style="color: black;">有些</span>良性<span style="color: black;">疾患</span>、女性怀孕、<span style="color: black;">大姨妈</span>以及肾脏<span style="color: black;">疾患</span>,都会影响<span style="color: black;">检测</span>的结果,<span style="color: black;">另外</span>,<span style="color: black;">倘若</span>肿瘤标志物只是一次轻度<span style="color: black;">上升</span>或每次<span style="color: black;">检测</span>的结果<span style="color: black;">无</span>大的变化,那<span style="color: black;">亦</span><span style="color: black;">能够</span>不必担心!</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">由此可见,肿瘤的诊断<span style="color: black;">不可</span>单独依靠肿瘤标志物的<span style="color: black;">检测</span>,单次肿瘤标志物<span style="color: black;">上升</span>的<span style="color: black;">道理</span>并不大,<span style="color: black;">仅有</span>动态的<span style="color: black;">连续</span><span style="color: black;">上升</span>才有<span style="color: black;">道理</span>。<span style="color: black;">针对</span>恶性肿瘤<span style="color: black;">病人</span><span style="color: black;">来讲</span>,任何一种恶性肿瘤都<span style="color: black;">无</span>绝对特异的肿瘤标志物,且<span style="color: black;">每一个</span><span style="color: black;">病人</span><span style="color: black;">针对</span><span style="color: black;">各样</span>肿瘤标志物都有各自的<span style="color: black;">基本</span>水平。<span style="color: black;">因此呢</span>,针对不同的<span style="color: black;">疾患</span>和不同的<span style="color: black;">病人</span><span style="color: black;">能够</span>有不同的肿瘤标志物<span style="color: black;">做为</span>其疗效监测的指标。当肿瘤经治疗有好转或因肿瘤复发转移而病情恶化时,这些肿瘤标志物水平的变化</p>
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