血液中可能有几百种癌症标记物,为么很难测出来?
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">癌症最<span style="color: black;">要紧</span>的是</span><span style="color: black;"><strong style="color: blue;">“早诊早治”。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">越早<span style="color: black;">发掘</span>,越早治疗,就越能成功地治疗癌症,<span style="color: black;">加强</span>治疗后的<span style="color: black;">存活</span>率。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">然则</span>,<span style="color: black;">因为</span>技术所限,<span style="color: black;">日前</span>的癌症<span style="color: black;">初期</span>检测<span style="color: black;">办法</span>只是针对一种或几种癌症,很难对所有癌症都进行筛查。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">非常多</span>癌症<span style="color: black;">病人</span>都是在<span style="color: black;">显现</span>症状后才进行检测,而这很容易</span><span style="color: black;"><strong style="color: blue;"><span style="color: black;">错失</span>最佳治疗<span style="color: black;">机会</span>,降低治疗后<span style="color: black;">存活</span>率</strong>。</span></p><span style="color: black;"><span style="color: black;">为何</span>多一些<span style="color: black;">可靠</span>的癌症<span style="color: black;">初期</span>检测<span style="color: black;">办法</span>这么难呢?</span><span style="color: black;">今天,</span><strong style="color: blue;"><span style="color: black;">健康榨知机</span></strong><span style="color: black;">就跟<span style="color: black;">大众</span>讲讲<span style="color: black;">暗地里</span>的<span style="color: black;">原由</span></span><span style="color: black;">↓↓↓</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">在血液中寻找癌症线索,没<span style="color: black;">那样</span>容易</span></strong></span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">近年来,<span style="color: black;">开发</span>出能够检测癌症的血液检测技术,<span style="color: black;">始终</span>是<span style="color: black;">专家</span>聚焦的<span style="color: black;">要紧</span><span style="color: black;">行业</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">非常多</span>人的想象是<span style="color: black;">这般</span>的——从人<span style="color: black;">身体</span>取一小瓶血液,<span style="color: black;">经过</span>检测,就能够在癌症<span style="color: black;">初期</span>和最佳治疗<span style="color: black;">周期</span><span style="color: black;">发掘</span>癌症</strong>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">这种想法<span style="color: black;">特别有</span>吸引力,<span style="color: black;">亦</span>是<span style="color: black;">专家</span>们正在积极探索的方向。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">但事实证明,尽管付出了很大的<span style="color: black;">奋斗</span>,还是很难找到一种<span style="color: black;">靠谱</span>、准确的血液检测<span style="color: black;">办法</span>来<span style="color: black;">帮忙</span><span style="color: black;">初期</span><span style="color: black;">发掘</span>癌症。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">想要在血液中寻找癌症的线索,绝不是容易的事。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/xlFoDVCgSYESEGN99icEaIj9oIHjPMVm3duxybI5BbzicGM5R66UODCkEUTclypMdM6AraXBI3iaVsASnTU5Z1Tcw/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">照片</span><span style="color: black;">源自</span>:123RF</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">首要</span>,癌症极其<span style="color: black;">繁杂</span>,有200多种类型,</span><span style="color: black;"><strong style="color: blue;">每种癌症都会释放几百种不同的标记物</strong></span><span style="color: black;">到血液中。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">其次,癌症的标记物在血液中并不是独立存在的,它们与<span style="color: black;">各样</span>健康细胞和其他分子共存于血液中,</span><span style="color: black;"><strong style="color: blue;">仅仅1毫升血液中就有大约50亿个红细胞</strong>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">第三,<span style="color: black;">日前</span>的血液</span><span style="color: black;"><strong style="color: blue;">检测<span style="color: black;">办法</span>缺乏<span style="color: black;">敏锐</span>性和特异性</strong></span><span style="color: black;">。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">检测结果可能<span style="color: black;">显现</span>假阴性,<span style="color: black;">亦</span><span style="color: black;">便是</span>误判一个癌症<span style="color: black;">病人</span>“<span style="color: black;">无</span>得癌症”;<span style="color: black;">亦</span>可能<span style="color: black;">显现</span>假阳性,误判一个本来<span style="color: black;">无</span>癌症的人“得了癌症”。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">总而言之,<strong style="color: blue;">想要在血液中<span style="color: black;">发掘</span>癌症,<span style="color: black;">尤其</span>是<span style="color: black;">初期</span>癌症,<span style="color: black;">没</span>异于大海捞针</strong>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">不外</span>,尽管探索的过程依然艰辛,<span style="color: black;">专家</span>们仍然<span style="color: black;">无</span>停下前进的脚步。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">血液中<span style="color: black;">为何</span>很难</span></strong></span></strong></span><span style="color: black;"><strong style="color: blue;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">找</span></strong></span></strong></span><strong style="color: blue;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">癌症的迹象</span></strong>?</span></strong></p>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">参考资料</p><span style="color: black;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"> Joshua D. Cohen, et al.(2018). Detection and localization of surgically resectable cancers with a multi-analyte blood test. CANCER, DOI:10.1126/science.aar3247.</p>
</span><span style="color: black;"> Blood tests: using blood to detect cancer early. Retrieved<span style="color: black;">Aug</span><span style="color: black;">9, </span><span style="color: black;">2022</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">from https://scienceblog.cancerresearchuk.org/2019/12/04/blood-tests-using-blood-to-detect-cancer-early/</p> Understanding Laboratory Tests. Retrieved Aug 9, 2022 from https://www.cancer.gov/about-cancer/diagnosis-staging/understanding-lab-tests-fact-sheet
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