原创 120万一针“抗癌神药”，已有400位病人运用，清零癌细胞真的值吗
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">你觉得癌症能被治愈吗？</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">仅仅三个月，全身肿瘤消失！</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">这到底是什么疗法？竟然能让绝境中的人病情完全缓解？</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">1、</span>一针清零癌细胞，真有<span style="color: black;">那样</span>神奇？</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">01、女儿两个多月，24岁的他确诊癌症</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">张鹏在一家电子厂上班，经常两班倒，一<span style="color: black;">起始</span>身体<span style="color: black;">显现</span><span style="color: black;">反常</span>的时候，他只以为是工作太累了，没想到后来症状越来越重，坐在工位上大喘气<span style="color: black;">亦</span>缓<span style="color: black;">不外</span>来，才请了假去医院<span style="color: black;">检测</span>，没想到却被<span style="color: black;">大夫</span><span style="color: black;">通知</span>是患了<strong style="color: blue;">白血病</strong>。</p><img src="//q9.itc.cn/images01/20240312/e1975e76f8b14c01825f4e983967699e.jpeg" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">他当时<span style="color: black;">全部</span>人都懵了，“<span style="color: black;">大夫</span>，你<span style="color: black;">是否</span>看错了，我才24岁，怎么可能有癌症”说完<span style="color: black;">心情</span>崩溃之下，直接在门诊里哭了起来。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">看了治疗<span style="color: black;">必须</span>的花费，他想死的心都有了，但家人<span style="color: black;">晓得</span>后，<span style="color: black;">无</span><span style="color: black;">抱怨</span>什么，只是把手头里的钱凑一凑，<span style="color: black;">不足</span>的再找亲朋好友借，就<span style="color: black;">这般</span><span style="color: black;">起始</span>了他的抗癌之路。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">02、用自己的细胞杀死肿瘤</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">张鹏回忆，<span style="color: black;">第1</span>次做造血干细胞移植治疗，只维持了2年就复发了，后来<span style="color: black;">大夫</span>又安排了二次移植术，但<span style="color: black;">火速</span><span style="color: black;">亦</span>以失败告终。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">两次移植都没能杀死癌细胞，他<span style="color: black;">晓得</span>这病是治<span style="color: black;">欠好</span>了。</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">“后来<span style="color: black;">亦</span>不害怕了，<span style="color: black;">更加多</span>的是麻木”</p><img src="//q8.itc.cn/images01/20240312/93e11b2b162f4538b24196e30adedc69.jpeg" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">想着反正<span style="color: black;">已然</span><span style="color: black;">这般</span>了，过一天是一天吧，只是<span style="color: black;">孩儿</span>还这么小，家里人<span style="color: black;">亦</span><span style="color: black;">由于</span>这病忙前忙后，欠下一大堆外债，觉得对不起家人。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">第二次复发后，他深知自己的生命要进入倒计时了，然而上天似乎并<span style="color: black;">无</span>放弃他，经院里专家综合诊疗，给他提出了<strong style="color: blue;">CAR-T细胞治疗<span style="color: black;">方法</span></strong>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">当时CAR-T治疗受技术和硬件<span style="color: black;">前提</span>限制还<span style="color: black;">无</span>大规模应用，<span style="color: black;">非常多</span>人还不<span style="color: black;">认识</span>其中应用机制。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">简单<span style="color: black;">来讲</span>，<span style="color: black;">便是</span><strong style="color: blue;">从<span style="color: black;">病人</span><span style="color: black;">身体</span>提取T细胞，体外培育成CAR-T细胞，再<span style="color: black;">传送</span>回<span style="color: black;">病人</span><span style="color: black;">身体</span></strong>，这些CAR-T细胞会<span style="color: black;">精细</span>定位肿瘤细胞并展开灭杀行动，达到治疗效果。</p><img src="//q9.itc.cn/images01/20240312/6aa77b0ef1e244379eed9953fd61b4c9.png" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">03、中国首例CAR-T治疗<span style="color: black;">病人</span>，<span style="color: black;">此刻</span>怎么样了</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">好在一切都值得，张鹏在治疗半个月后，<strong style="color: blue;"><span style="color: black;">身体</span>肿瘤细胞<span style="color: black;">已然</span>基本清零</strong>，<span style="color: black;">况且</span><span style="color: black;">亦</span><strong style="color: blue;">顺利度过了5年<span style="color: black;">存活</span>期</strong>，“<span style="color: black;">能够</span>说是完全治愈了。”</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">每次回想起这件事，他就非常感慨，当时这项技术还属于临床<span style="color: black;">科研</span><span style="color: black;">周期</span>，谁<span style="color: black;">亦</span><span style="color: black;">不可</span><span style="color: black;">保准</span><span style="color: black;">必定</span>成功，<span style="color: black;">亦</span><span style="color: black;">便是</span>死马当活马医了，没想到<span style="color: black;">此刻</span>想做得花120万。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">由于</span>CAR-T治疗在治疗血液系统肿瘤带来的突破性<span style="color: black;">发展</span>，受到了广泛的关注，<span style="color: black;">日前</span>大部分临床<span style="color: black;">实验</span>数据都<span style="color: black;">表现</span>了很好的疗效。</p><img src="//q6.itc.cn/images01/20240312/8b9aa23821ee41d48b92a655179be4a0.jpeg" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">2、</span><span style="color: black;">为么</span>CAR-T治疗<span style="color: black;">花费</span><span style="color: black;">昂贵</span>？</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">截止</span><span style="color: black;">日前</span>，<span style="color: black;">全世界</span>范围内被正式<span style="color: black;">准许</span>上市的CAR-T疗法，有6款在海外，国内有2款，<span style="color: black;">况且</span>自2021年先后<span style="color: black;">获准</span>后，<strong style="color: blue;">累计治疗了400位<span style="color: black;">病人</span></strong>，<span style="color: black;">营销</span>额合计约5亿元人民币。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">亦</span>许有人会觉得，2年才400个人接受了治疗，<span style="color: black;">是否</span>市场<span style="color: black;">欠好</span>？</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">其实非<span style="color: black;">亦</span>，<span style="color: black;">重点</span>是<span style="color: black;">由于</span>治疗<span style="color: black;">花费</span>太贵，不是<span style="color: black;">每一个</span>家庭都能马上拿出120万的！至于<span style="color: black;">为何</span>该疗法价格这么高，其实<span style="color: black;">能够</span>归为两个<span style="color: black;">原由</span>：</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">1、独家定制</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">CAR-T是<span style="color: black;">按照</span>个人量身定制的疗法，<span style="color: black;">每一个</span><span style="color: black;">病人</span><span style="color: black;">最后</span>的注射液都不<span style="color: black;">同样</span>，<span style="color: black;">由于</span><strong style="color: blue;"><span style="color: black;">没</span>法批量生产</strong>，自然成本就<span style="color: black;">提升</span>了，加上CAR-T治疗适用范围不大，<span style="color: black;">亦</span>难以规模化应用。</p><img src="//q4.itc.cn/images01/20240312/f107552866364dabbe165dd4e2b11bf5.jpeg" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">2、技术<span style="color: black;">需求</span>高</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">这项治疗技术对人员配备<span style="color: black;">需求</span>非常高，<span style="color: black;">没</span>论是前期免疫细胞提取还是注射CAR-T<span style="color: black;">药品</span>，前后都<span style="color: black;">必须</span>专业的医疗人员操作，这就<span style="color: black;">需求</span>治疗团队符合高水准的临床护理<span style="color: black;">前提</span>，花费自然<span style="color: black;">亦</span>就水涨船高。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">复星国际执行董事兼联席CEO陈启宇曾<span style="color: black;">暗示</span>“CAR-T<span style="color: black;">制品</span>生产单是员工培训成本<span style="color: black;">便是</span>30万元人民币。”</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">况且</span>CAR-T细胞治疗<span style="color: black;">拥有</span>个性化定制属性，从细胞采集到后期培养、<span style="color: black;">贮存</span>、质量<span style="color: black;">掌控</span><span style="color: black;">全部</span>流程都有很高技术<span style="color: black;">需求</span>，每一个环节都<span style="color: black;">寓意</span>着成本。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">上海交通大学医学院<span style="color: black;">附庸</span>瑞金医院副院长、血液内科常务副<span style="color: black;">专家</span>赵维莅</strong><span style="color: black;">暗示</span>，虽然CAR-T治疗价格高、成本<span style="color: black;">亦</span>高，但<span style="color: black;">将来</span>随着<span style="color: black;">药物</span>生产流程<span style="color: black;">持续</span>改进，后期价格<span style="color: black;">亦</span>会有所降低。</p><img src="//q5.itc.cn/images01/20240312/f1f21d96fb4740ac9dd1ad742c769218.jpeg" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">3、</span>“120万的神药”真的值得吗？需理性对待</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">CAR-T细胞治疗虽然疗效卓异，但并非万能<span style="color: black;">办法</span>，它的适应证有限，<span style="color: black;">日前</span><strong style="color: blue;">只适用于部分血液肿瘤</strong>，其他大<span style="color: black;">都数</span>实体瘤还<span style="color: black;">不可</span>应用。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">况且</span><span style="color: black;">亦</span>有<span style="color: black;">必定</span>不良反应几率，<span style="color: black;">科研</span><span style="color: black;">显示</span>，<span style="color: black;">病人</span>接受治疗过程中<strong style="color: blue;">都<span style="color: black;">显现</span>了不同程度的毒副<span style="color: black;">功效</span></strong>，<span style="color: black;">例如</span>细胞因子释放<span style="color: black;">综合症</span>等，<span style="color: black;">重点</span>表现为发热，严重可能<span style="color: black;">引起</span>全身炎症反应、血压低、<span style="color: black;">呼气</span>困难和器官<span style="color: black;">衰尽</span>等。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">还有的人会<span style="color: black;">显现</span><span style="color: black;">剧烈</span>的神经毒性反应，<span style="color: black;">显现</span><span style="color: black;">认识</span>模糊、抽搐、癫痫等症状，<span style="color: black;">病人</span>还会<span style="color: black;">显现</span>不同程度的记忆力衰退<span style="color: black;">状况</span>。</p><img src="//q8.itc.cn/images01/20240312/562a77622d284f37b3062b8789bc08a6.jpeg" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">针对</span>网上流传的“120万元打一针，2个月癌细胞清零”的说法，官方<span style="color: black;">亦</span>出面辟谣，<span style="color: black;">暗示</span>该免疫疗法效果<span style="color: black;">无</span><span style="color: black;">那样</span>夸张，<strong style="color: blue;">完全缓解不<span style="color: black;">表率</span>治愈</strong>，<span style="color: black;">况且</span>该技术<span style="color: black;">日前</span>还<span style="color: black;">处在</span>临床<span style="color: black;">初期</span>应用，并不是所有癌症都适用！</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">相反<span style="color: black;">媒介</span>过渡渲染很可能误导公众，<span style="color: black;">引起</span><span style="color: black;">病人</span>蜂拥而至，<span style="color: black;">增多</span>医疗接待<span style="color: black;">包袱</span>之余，还可能让有心之人嗅到可乘之机，利用<span style="color: black;">病人</span>求治心理大肆<span style="color: black;">谋财</span>，<span style="color: black;">诱发</span>更严重的社会乱象。</p><img src="//q9.itc.cn/images01/20240312/8af5c64773734f2b8c5b06e339ae9a95.jpeg" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">总而言之，CAR-T免疫治疗并不是万金油疗法，虽然治疗效果有<span style="color: black;">必定</span>突破性表现，但仍需理性看待，切不可<span style="color: black;">茫然</span>跟风，<span style="color: black;">导致</span>其他不必要的损失。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">参考资料：</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">《【专论】血液肿瘤中CAR-T细胞疗法的<span style="color: black;">状况</span>及优化策略》.中华内科杂志.2023-06-13.</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">《"120万元一针的药或让癌细胞清零"<span style="color: black;">到底</span>是真是假？今天都给你说明白》.科普中国. 2021-10-02.</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">《“抗癌神药120万一针”？》.新京报.2021-10-15.</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">未经作者<span style="color: black;">准许</span>授权，禁止转载<a style="color: black;"><span style="color: black;">返回首页，查看<span style="color: black;">更加多</span></span></a></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">外链论坛：http://www.fok120.com/</p>
这篇文章真的让我受益匪浅，外链发布感谢分享！ 说得好啊！我在外链论坛打滚这么多年，所谓阅人无数，就算没有见过猪走路，也总明白猪肉是啥味道的。
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