原创 多发性骨髓瘤危不危险?看这些指标
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">多发性骨髓瘤在医学临床上有一套完整的病情<span style="color: black;">评定</span>指南(<span style="color: black;">重点</span>结合FISH结果),用来<span style="color: black;">初期</span>定义病情危险程度,进一步确定治疗<span style="color: black;">机会</span>以及<span style="color: black;">知道</span>合适的治疗<span style="color: black;">方法</span>。<span style="color: black;">针对</span>多发性骨髓瘤病情的危险等级划分,下文进行<span style="color: black;">关联</span>解析!</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">多发性骨髓瘤危不危险?看这些指标</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="//q3.itc.cn/q_70/images01/20240223/a66dbffb0ccd4313870e4a6308191be4.png" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">经过</span><span style="color: black;">关联</span>实验室结果来定义骨髓瘤标危与高危的危险度分层,而这项结果<span style="color: black;">亦</span>直接关乎到了病人的治疗<span style="color: black;">方法</span><span style="color: black;">选取</span>以及<span style="color: black;">将来</span>的<span style="color: black;">存活</span>期长短。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">标危多发性骨髓瘤指标:</strong>①三倍体;②遗传学<span style="color: black;">反常</span>t(11;14)与t(6;14)。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">标危多发性骨髓瘤指标:</strong>①遗传学<span style="color: black;">反常</span>t(4;14)、t(14;16)、t(14;20)、Del 17p、P53突变、Iq扩增;②RISS III期、高S期浆细胞;③基因表达谱呈现高危信号。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">综上,被<span style="color: black;">评定</span>为标危的骨髓瘤<span style="color: black;">病人</span>可走常规标准的治疗指南,高危多发性骨髓瘤<span style="color: black;">必须</span><span style="color: black;">导致</span>高度<span style="color: black;">注意</span>,<span style="color: black;">寓意</span>着病情发展速度容易加快以及用药耐性差,<span style="color: black;">必须</span><span style="color: black;">按照</span>FISH结果来<span style="color: black;">调节</span>适合的治疗<span style="color: black;">方法</span>,来争取达到进一步可观的缓解效果。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="//q2.itc.cn/q_70/images01/20240223/56bc5733c23b4140a81e5917c4de8da3.png" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">另一</span><span style="color: black;">亦</span><span style="color: black;">思虑</span>到大多高危多发性骨髓瘤<span style="color: black;">病人</span>自主感觉症状<span style="color: black;">明显</span>,<span style="color: black;">存活</span>质量<span style="color: black;">不良</span>等<span style="color: black;">原因</span>,在高强度治疗的<span style="color: black;">同期</span>还<span style="color: black;">必须</span>避免一味的下猛药,避免<span style="color: black;">病人</span>身体承受不住反而加重病情,贯彻“先有人,再治病”的原则。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">本文来自<span style="color: black;">微X</span>公众号:MPD病友会</strong><a style="color: black;"><span style="color: black;">返回<span style="color: black;">外链论坛:http://www.fok120.com/</span>,查看<span style="color: black;">更加多</span></span></a></p>
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