为么癌症经过治疗几年后还会复发？原由找到了......
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">癌症的再次复发<span style="color: black;">始终</span>是抗击癌症过程中的一个<span style="color: black;">困难</span>，<span style="color: black;">作为</span><span style="color: black;">病人</span>和<span style="color: black;">大夫</span>的心头大患。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">为何</span>在<span style="color: black;">初期</span><span style="color: black;">发掘</span>的癌症经过成功的治疗后，几年之后还会复发？难道狡猾的癌细胞在<span style="color: black;">各样</span>治疗之后死灰复燃？</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">在人们<span style="color: black;">一般</span>的认知中，肿瘤细胞在人<span style="color: black;">身体</span>不受<span style="color: black;">掌控</span>且<span style="color: black;">快速</span>增长，<span style="color: black;">此刻</span>看来这可能是个”错误“的认知。最新的<span style="color: black;">科研</span><span style="color: black;">显示</span>，</span><strong style="color: blue;"><span style="color: black;">癌细胞会<span style="color: black;">运用</span>“油门”和“刹车”两个控件来<span style="color: black;">掌控</span>自己的<span style="color: black;">存活</span>周期，从而在<span style="color: black;">繁杂</span>的人体环境中<span style="color: black;">存活</span>下来。</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">01</span></strong></span></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">不可想象：癌细胞竟然会休眠</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">咱们</span>都<span style="color: black;">晓得</span><span style="color: black;">有些</span>动物会在冬天的时候冬眠，<span style="color: black;">经过</span>降低体温的方式而进入类似昏睡的生理状态，它们会深居巢穴，<span style="color: black;">很难</span>被<span style="color: black;">发掘</span>。想象一下<span style="color: black;">倘若</span>癌细胞<span style="color: black;">经过</span></span><strong style="color: blue;"><span style="color: black;">休眠</span></strong><span style="color: black;">的方式，藏匿在身体的某些<span style="color: black;">地区</span>，在几年后“醒来”<span style="color: black;">起始</span>形成新的肿瘤，复发<span style="color: black;">危害</span>不可避免。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://q8.itc.cn/q_70/images03/20240502/f1878d08157d4b5cbea56c4db97baea7.png" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">照片</span><span style="color: black;">表示</span>随着时间的推移，前列腺癌细胞休眠期与快速生<span style="color: black;">长时间</span>交替的例子。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">早在2018年来自英国的Francesco Crea教授就在《the conversation》<span style="color: black;">网</span>上面向<span style="color: black;">咱们</span>展示了狡猾的癌细胞的<span style="color: black;">存活</span>周期。当肿瘤快速生长，并且让身体产生症状，<span style="color: black;">病人</span><span style="color: black;">此时</span>候才会发觉，到医院进行<span style="color: black;">检测</span>和一系列的治疗<span style="color: black;">干涉</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">但癌细胞<span style="color: black;">怎样</span>苏醒的机制<span style="color: black;">日前</span>还尚不清楚。此前有<span style="color: black;">科研</span><span style="color: black;">发掘</span>，<span style="color: black;">连续</span>的肺部炎症可能是唤醒癌细胞的一个<span style="color: black;">原因</span>。<span style="color: black;">科研</span>人员将小鼠暴露于烟草烟雾或<span style="color: black;">叫作</span>为内毒素的细菌<span style="color: black;">成份</span>中，会<span style="color: black;">引起</span>嗜中性白细胞以一种特殊的方式唤醒<span style="color: black;">周边</span>休眠的癌细胞，促进癌细胞的增长。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">而近期一项<span style="color: black;">发布</span>在国际杂志《Science Translational Medicine》上的<span style="color: black;">科研</span>报告中指出，癌症的治疗方式并<span style="color: black;">不可</span>完全杀死<span style="color: black;">所有</span>的癌细胞，有些癌细胞会移动到较远的位置</span><span style="color: black;"><strong style="color: blue;">“休眠”</strong></span><span style="color: black;">，躲避“追杀”，当外界有压力激素产生时，它们会被</span><strong style="color: blue;"><span style="color: black;">“唤醒”</span></strong><span style="color: black;">，癌症复发由此产生。如此来看，</span><strong style="color: blue;"><span style="color: black;">压力太大竟会<span style="color: black;">引起</span>癌症复发！</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">02</span></strong></span></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">压力<span style="color: black;">作为</span>癌症复发的罪魁祸首</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">对大部分人而言，适当的压力可能<span style="color: black;">加强</span>人的警觉性，使其更小心思考，<span style="color: black;">小心</span>行事，从而发挥更理想的表现。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">但过度的压力则会使其<span style="color: black;">困惑</span>、<span style="color: black;">懊丧</span>和气馁，引致压力激素（如肾上腺素、去甲肾上腺素（NE）、皮质醇和血清素）<span style="color: black;">增加</span>，失去自控能力，影响身体健康。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://q5.itc.cn/q_70/images03/20240502/fc9a338a8bef4ea1af78a915520329dc.jpeg" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">照片</span><span style="color: black;">源自</span>：图虫创意</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">在上文中<span style="color: black;">说到</span>，炎症反应可能会促进癌细胞的增长，这是<span style="color: black;">由于</span>当炎症产生时，<span style="color: black;">拥有</span>免疫<span style="color: black;">控制</span>功能的多形核中性粒细胞（PMN ）被激活，<span style="color: black;">叫作</span>为多形核髓源<span style="color: black;">控制</span>细胞（ PMN-MDSC）。而PMN-MDSC<span style="color: black;">能够</span>产生产生免疫<span style="color: black;">控制</span>因子，<span style="color: black;">经过</span><span style="color: black;">控制</span>免疫反应 “<span style="color: black;">帮助</span>” 癌细胞逃避免疫攻击。炎症反应就<span style="color: black;">成为了</span>肿瘤生长的</span>“<span style="color: black;">走狗</span>”<span style="color: black;">。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">然则</span>压力与PMN-MDSC有什么关系呢？为了搞清楚这一联系，<span style="color: black;">科研</span>人员做了一系列的实验。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">最新的实验结果<span style="color: black;">表示</span>，压力激素能够<span style="color: black;">导致</span> PMN <span style="color: black;">快速</span>释放 S100A8/A9蛋白，</span><strong style="color: blue;"><span style="color: black;"><span style="color: black;">从而</span><span style="color: black;">导致</span>休眠癌细胞的再激活。</span></strong><span style="color: black;">这说明压力激素可能<span style="color: black;">经过</span>介导 PMN 释放 S100A8/A9，产生和PMN-MDSC<span style="color: black;">同样</span>的效果，<span style="color: black;">帮助</span>癌细胞逃过攻击，从而激活休眠癌细胞 。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">为了验证这一<span style="color: black;">发掘</span>，<span style="color: black;">她们</span>将压力激素注射到携带休眠癌细胞的小鼠<span style="color: black;">身体</span>，<span style="color: black;">发掘</span>这些小鼠的肿瘤<span style="color: black;">出现</span>率<span style="color: black;">显著</span><span style="color: black;">提升</span>，并观察到了癌细胞的苏醒和繁殖。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">不仅如此，在80名接受手术治疗的肺癌<span style="color: black;">病人</span>的血清样本中，<span style="color: black;">科研</span>人员<span style="color: black;">发掘</span>血清中 S100A8/A9 浓度高的病人癌症复发时间<span style="color: black;">显著</span>更短。</span><span style="color: black;"><strong style="color: blue;"><span style="color: black;">亦</span><span style="color: black;">便是</span>说，携带高水平S100A8/A9蛋白的肺癌<span style="color: black;">病人</span>再次复发的<span style="color: black;">危害</span>更高。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">综上来看，压力<span style="color: black;">引起</span>癌症复发的<span style="color: black;">原由</span>应该是<span style="color: black;">这般</span>的：压力激素<span style="color: black;">引起</span>PMN<span style="color: black;">快速</span>释放S100A8/A9蛋白，S100A8/A9 激活髓过氧化物酶（MPO），又经历了<span style="color: black;">有些</span>列的修饰反应，从而使癌细胞重新被激活并形成新的肿瘤。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">虽然<span style="color: black;">科研</span>人员<span style="color: black;">意见</span>给癌症<span style="color: black;">病人</span><span style="color: black;">运用</span>β受体阻滞剂，可能会预防某些类型癌症的复发。但<span style="color: black;">疾患</span>产生的机制错综<span style="color: black;">繁杂</span>，<span style="color: black;">咱们</span><span style="color: black;">亦</span>不清楚每一个<span style="color: black;">过程</span>，但<span style="color: black;">科研</span>的结果<span style="color: black;">亦</span>给了<span style="color: black;">咱们</span>一个很大的启发，</span><strong style="color: blue;"><span style="color: black;">想要降低癌症的复发<span style="color: black;">危害</span>，摆脱压力是<span style="color: black;">重要</span>。</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">03</span></strong></span></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">让自己快乐起来</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">针对</span>健康人而言，压力太大不是个好东西。<span style="color: black;">长时间</span><span style="color: black;">处在</span>压力下的人容易<span style="color: black;">显现</span>一系列<span style="color: black;">疾患</span>，从而形成一个压力恶化病情，病情又带来<span style="color: black;">更加多</span>压力的恶性循环。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">病患</span>癌症的人则承受着双重压力，一方面来自与癌症抗争所带来的心理创伤，另一方面<span style="color: black;">亦</span>是来<span style="color: black;">自己</span>体承受的压力，例如<span style="color: black;">病人</span>接受的<span style="color: black;">各样</span>治疗。有<span style="color: black;">科研</span>认为，化疗和手术，都能给<span style="color: black;">病人</span>的身体和心理带来<span style="color: black;">必定</span>的损害。<span style="color: black;">因此呢</span>，癌症<span style="color: black;">病人</span>要学会释放压力。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">1、</span><span style="color: black;">宣泄心情</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">科研</span><span style="color: black;">发掘</span>，<span style="color: black;">非常多</span>癌症病友多<span style="color: black;">拥有</span>C型性格特征，即很容易产生失望和悲观的消极<span style="color: black;">心情</span>，过分克制压抑<span style="color: black;">心情</span>，缺乏表达爱的能力，这些特征对抗癌其实是一大阻碍。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">仅有</span>把内心的痛苦表达出来，让这些<span style="color: black;">消极</span><span style="color: black;">心情</span>得到宣泄<span style="color: black;">才可</span>真正摆脱抑郁，走向情感升华期，学会积极<span style="color: black;">阳光</span>抗癌。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">2、<span style="color: black;">保持</span>你的<span style="color: black;">兴趣</span></span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">当一个人<span style="color: black;">处在</span>焦虑<span style="color: black;">或</span>紧张的时候，<span style="color: black;">咱们</span>很容易把兴趣<span style="color: black;">兴趣</span>放在一边，<span style="color: black;">而后</span>专注在<span style="color: black;">咱们</span>觉得<span style="color: black;">要紧</span>的事上。<span style="color: black;">然则</span>这反而会让你更加紧张。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">正确的做法应该重新拾起你旧时的<span style="color: black;">兴趣</span>，阅读期刊<span style="color: black;">亦</span>好，观看球赛，跳舞<span style="color: black;">亦</span>好。给自己一点时间做<span style="color: black;">爱好</span>的事，会让你觉得神清气爽。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">对之前本就<span style="color: black;">无</span>什么<span style="color: black;">兴趣</span>的觅友，则<span style="color: black;">能够</span>尝试挑一个自己感兴趣的活动，<span style="color: black;">例如</span>语言，手工艺，插花，练毛笔等，学习新的东西有时候会让你更放松。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">3、向癌症发起挑战</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">亦</span>许，<span style="color: black;">此刻</span>还不确定自己的预后<span style="color: black;">怎样</span>，<span style="color: black;">将来</span>该<span style="color: black;">怎样</span>安排，但有一点要记住：面对<span style="color: black;">疾患</span>，<span style="color: black;">仅有</span>不屈服，<span style="color: black;">才可</span>战胜。面对癌症<span style="color: black;">亦</span>是一</span><span style="color: black;">样，<span style="color: black;">仅有</span><span style="color: black;">阳光</span>豁达、勇于挑战<span style="color: black;">才可</span>调动肌体潜能、<span style="color: black;">加强</span>免疫功能，发挥抗癌<span style="color: black;">功效</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">当然，心理调适的<span style="color: black;">同期</span>，</span><span style="color: black;"><strong style="color: blue;"><span style="color: black;">亦</span>要<span style="color: black;">重视</span>生理调节，就从处理身边的小事做起。</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">在病房很容易见到<span style="color: black;">非常多</span>家属照顾的<span style="color: black;">没</span>微不至，连挤牙膏、系鞋带<span style="color: black;">这般</span>的小事都包办了，这虽然是爱的表现，但极易使<span style="color: black;">病人</span>认为自己是个废人，丧失<span style="color: black;">自信心</span>，认为自己<span style="color: black;">已然</span>进入了生命的“倒计时”。<span style="color: black;">因此</span>，让<span style="color: black;">病人</span>处理身边的小事势在必行。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">当能做到生活自理，就该<span style="color: black;">起始</span>逐步<span style="color: black;">熬炼</span>身体，<span style="color: black;">能够</span>先从散步做起。适当的活动不仅能使身体得到直接<span style="color: black;">熬炼</span>，还能有助于<span style="color: black;">病人</span>从压抑、焦虑中<span style="color: black;">摆脱</span>出来。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">在这些调节中，<span style="color: black;">病人</span>的心理会向积极的良性<span style="color: black;">心情</span>转变，学会精神放松的正确<span style="color: black;">办法</span>。<span style="color: black;">经过</span>心理调节和生理调节的协同<span style="color: black;">功效</span>，<span style="color: black;">加强</span>癌症<span style="color: black;">病人</span>的生活质量和延长<span style="color: black;">存活</span>期。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">肺癌</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">《事关<span style="color: black;">医疗保险</span>报销！肺癌<span style="color: black;">病人</span>要做基因检测，千万别漏看这些省钱条例》</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">《用上这个药后，62%的肺癌<span style="color: black;">病人</span>肿瘤<span style="color: black;">显著</span>缩小或消失》</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">《从确诊肺癌到抗癌20年，她说癌细胞其实最怕你迈出这一步》</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">参考文献</strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">.https://theconversation.com/why-cancer-cells-go-to-sleep-949562.</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">.https://medicalxpress.com/news/2018-09-cancer-awakens-metastasizes.html</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">.Perego M, Tyurin VA, Tyurina YY, Yellets J, Nacarelli T, Lin C, Nefedova Y,Kossenkov A, Liu Q, Sreedhar S, Pass H, Roth J, Vogl T, Feldser D, Zhang R,Kagan VE, Gabrilovich DI. Reactivation of dormant tumor cells by modified lipidsderived from stress-activated neutrophils. Sci Transl Med. 2020 Dec2;12(572):eabb5817.</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">内容制作</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">封面<span style="color: black;">照片</span>：觅健</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">外链论坛：http://www.fok120.com/觅健科普君</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"> 我深感你的理解与共鸣，愿对话长流。 “BS”（鄙视的缩写） 论坛的成功是建立在我们诚恳、务实、高效、创新和团结合作基础上，我们要把这种精神传递下去。 谷歌网站排名优化 http://www.fok120.com/ 感谢楼主分享，祝愿外链论坛越办越好！
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