艾滋病最后会治愈吗?并不必定!
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">有些事情听起来并没<span style="color: black;">那样</span>美好,但它是现实,<span style="color: black;">例如</span>艾滋病会治愈吗?<span style="color: black;">并不</span><span style="color: black;">必定</span>!</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">近期</span>艾滋病治愈的<span style="color: black;">资讯</span>频频<span style="color: black;">显现</span>,<span style="color: black;">针对</span>一个感染了很久的老病友<span style="color: black;">来讲</span>,估计都懒得看,<span style="color: black;">由于</span><span style="color: black;">她们</span>大部分<span style="color: black;">已然</span>被治愈的<span style="color: black;">资讯</span>折腾的麻木了。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">治愈<span style="color: black;">资讯</span>每隔一段时间必然会<span style="color: black;">显现</span>,字眼常常会有“曙光”、“突破”、“即将”……<span style="color: black;">非常多</span>感染者乐此不疲的分享,仿佛马上要<span style="color: black;">摆脱</span>了。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">只是曙光转化成<span style="color: black;">咱们</span>头顶上的太阳,真的差了好远好远。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">基因疗法、免疫疗法、细胞疗法等等这些<span style="color: black;">办法</span>,<span style="color: black;">常常</span>只是提出一个概念就<span style="color: black;">起始</span>在网络上大肆传播,收割一大波的热情后就偃旗息鼓了,<span style="color: black;">而后</span>换<span style="color: black;">另一</span>一个概念继续收割。<span style="color: black;">咱们</span>就如同站在海边的婴儿<span style="color: black;">同样</span>,看着一波波海浪向<span style="color: black;">咱们</span>冲刷过来,<span style="color: black;">欢快</span><span style="color: black;">亦</span>此起彼伏,一下接着一下。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">根据新药<span style="color: black;">开发</span>的正常规律而言,提出设想到<span style="color: black;">最后</span>变成治疗<span style="color: black;">药品</span>,<span style="color: black;">必须</span>一个完整的生命周期,这个生命周期基本会在10-20年,<span style="color: black;">况且</span><span style="color: black;">开发</span><span style="color: black;">花费</span>以亿元美金来计,中间任何一个环节出错都有可能前功尽弃。</p><img src="data:image/svg+xml;utf8," style="width: 50%; margin-bottom: 20px;">新药<span style="color: black;">开发</span>流程<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">咱们</span>每年<span style="color: black;">准许</span>的原创生物药<span style="color: black;">亦</span>仅有1-2个,一位<span style="color: black;">伴侣</span>现就职于一家原创生物药<span style="color: black;">机构</span>,<span style="color: black;">机构</span>成立二十余年,<span style="color: black;">迄今</span><span style="color: black;">亦</span>仅有一款产品。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">因此</span><span style="color: black;">倘若</span>仅仅是停留在概念<span style="color: black;">或</span>单独案例,那真的还非常遥远。<span style="color: black;">另一</span>再加上艾滋病的病毒变异速度快、病毒<span style="color: black;">隐藏</span>深等特点,这些特点<span style="color: black;">日前</span>还<span style="color: black;">无</span>突破性的技术能<span style="color: black;">处理</span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">针对</span><span style="color: black;">近期</span>流传的细胞疗法,鸡尾酒疗法发明人何大一在2019年药明康德健康产业论坛上说过“现<span style="color: black;">周期</span>艾滋病<span style="color: black;">没</span>法治愈,虽然细胞疗法<span style="color: black;">科研</span>的如火如荼,<span style="color: black;">然则</span>这种方式尚未成熟”。</p><img src="data:image/svg+xml;utf8," style="width: 50%; margin-bottom: 20px;">何大一在2019药明康德健康产业论坛演讲<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">针对</span><span style="color: black;">已然</span>治愈的“柏林病人”、“伦敦病人”该怎么解释呢?这只能算是“奇迹”,这两位病人一位患白血病、一位患癌症,均接受了骨髓移植,并且移植均来自CCR5蛋白突变的供体。骨髓移植成功+突变基因这两种<span style="color: black;">原因</span>叠加的概率仅为0.0000001。<span style="color: black;">因此</span>这种治愈<span style="color: black;">办法</span>只是<span style="color: black;">供给</span>了<span style="color: black;">科研</span>方向,<span style="color: black;">没</span>法广泛推广。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">艾滋病肉眼可见的<span style="color: black;">不可</span>治愈,<span style="color: black;">那样</span><span style="color: black;">咱们</span>还能奢求什么呢?</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">虽然<span style="color: black;">无</span>治愈,<span style="color: black;">然则</span>艾滋病<span style="color: black;">已然</span><span style="color: black;">作为</span>一个可控的慢性病,北京协和医院艾滋病专家李太生说“联合用药(鸡尾酒疗法)<span style="color: black;">已然</span>让艾滋病接近治愈”。<span style="color: black;">日前</span>大部分<span style="color: black;">科研</span>方向并非“治愈”,而是<span style="color: black;">开发</span>更好的治疗方式和更好的<span style="color: black;">药品</span>,<span style="color: black;">例如</span>长效<span style="color: black;">药品</span>。</p><img src="data:image/svg+xml;utf8," style="width: 50%; margin-bottom: 20px;">我国首个抗艾滋病长效融合<span style="color: black;">控制</span>剂<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">从世界病毒史来看,病毒的消亡<span style="color: black;">亦</span>并非<span style="color: black;">仅有</span>治愈这一条。例如<span style="color: black;">已然</span>消失的天花病毒,其实<span style="color: black;">迄今</span><span style="color: black;">亦</span><span style="color: black;">无</span>治愈的<span style="color: black;">办法</span>,<span style="color: black;">然则</span><span style="color: black;">由于</span>有牛痘这种免疫法,让天花<span style="color: black;">已然</span>彻底灭绝了;还有<span style="color: black;">咱们</span>经历过的非典SARS病毒,<span style="color: black;">亦</span>是在<span style="color: black;">无</span>治愈的方式下消失的;麻风病、鼠疫、霍乱等等<span style="color: black;">疾患</span>虽然<span style="color: black;">此刻</span><span style="color: black;">无</span>彻底消亡,<span style="color: black;">然则</span>做到了可控可治,不<span style="color: black;">亦</span>渐渐式微了吗?</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">倘若</span>哪一天艾滋病治愈了,请<span style="color: black;">安心</span>,你绝对不是最后一个<span style="color: black;">晓得</span>的。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">此刻</span>仍然有<span style="color: black;">非常多</span>感染者,非常寄<span style="color: black;">期盼</span>于治愈,<span style="color: black;">期盼</span>自己彻底摆脱这个带有污名和<span style="color: black;">卑视</span>的病毒。在每次看到治愈<span style="color: black;">资讯</span>的时候,都激动不已,<span style="color: black;">乃至</span>都觉得<span style="color: black;">日前</span>自己<span style="color: black;">状况</span>都是临时的,治愈之后才会回归真正的自己。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">心存<span style="color: black;">期盼</span><span style="color: black;">然则</span>别<span style="color: black;">茫然</span><span style="color: black;">阳光</span>,做好<span style="color: black;">此刻</span>的自己吧!</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">本文原发于公号“张大花是个男生”</p>
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